null

SMILES CC(C)(C)c1cc(C=C2SC(NC#N)=NC2=O)cc(c1O)C(C)(C)C

InChI Key InChIKey=QHJVYZBKWNABSG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50044079   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50044079(5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calciumionophore A-23,187More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28C9V9PPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50044079(5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+4nMAssay Description:IC50 against recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X56Z3PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50044079(5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:IC50 value was determined against Prostaglandin G/H synthase 2 of J7744A.1 cell lines.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X56Z3PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50044079(5-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:IC50 against Prostaglandin G/H synthase 1 from human platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X56Z3PubMed