null

SMILES Clc1ccc(NC(=O)c2ccc3[nH]ncc3c2)cc1Cl

InChI Key InChIKey=IQCPUPDYBUPHRL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50046950   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
NTZ Lab Ltd.

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)copy SMILEScopy InChI
Affinity DataKi:  0.260nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1WFMPubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
NTZ Lab Ltd.

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)copy SMILEScopy InChI
Affinity DataIC50: 0.586nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2R0DPubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat recombinant MAO-A expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2R0DPubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
NTZ Lab Ltd.

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of MAOB in Sprague-Dawley rat liver mitochondria using p-tyramine as substrate measured for 45 mins in presence of MAOA inhibitor clorgyli...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9M6PPubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
NTZ Lab Ltd.

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)copy SMILEScopy InChI
Affinity DataIC50: 0.586nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus-infected BTI insect cells using p-tyramine as substrate measured for 45 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9M6PPubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
NTZ Lab Ltd.

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)copy SMILEScopy InChI
Affinity DataIC50: 0.589nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1WFMPubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
NTZ Lab Ltd.

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of rat recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2R0DPubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50046950(CHEMBL3319244)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAOA in Sprague-Dawley rat liver mitochondria using p-tyramine as substrate measured for 45 mins in presence of MAOB inhibitor selegili...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9M6PPubMed