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SMILES CCCCCn1c(N)nc2c(C)cccc12

InChI Key InChIKey=BWGFTWWXYOBSIL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056698   

TargetToll-like receptor 8(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50056698(CHEMBL3326930)copy SMILEScopy InChI
Affinity DataEC50:  1.13E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9S3SPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50056698(CHEMBL3326930)copy SMILEScopy InChI
Affinity DataEC50:  1.13E+3nMAssay Description:Antagonist activity at serotonin 5HT2A receptor assessed as effect on 5HT-induced isometric contractile force in isolated rings of pig coronary arter...More data for this Ligand-Target Pair
In DepthDetails
TargetToll-like receptor 8(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50056698(CHEMBL3326930)copy SMILEScopy InChI
Affinity DataEC50:  1.13E+3nMAssay Description:Agonist activity at at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z3FPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50056698(CHEMBL3326930)copy SMILEScopy InChI
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106NXPubMed