null

SMILES CN1C2=NC3(CCCC3)CN2c2nc(Cc3ccc(cc3)-c3ccccc3)n(Cc3ccccc3)c2C1=O

InChI Key InChIKey=RRRMTTFOHGYQIH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50059026   

TargetPhosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059026(5'-Methyl-2'-(biphenylmethyl)-3'-(phenylmethyl)spi...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heartMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44PFZPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059026(5'-Methyl-2'-(biphenylmethyl)-3'-(phenylmethyl)spi...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Evaluated for inhibitory activity against Phosphodiesterase 5 (PDE5) purified from bovine lungMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44PFZPubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059026(5'-Methyl-2'-(biphenylmethyl)-3'-(phenylmethyl)spi...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44PFZPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Dart Neuroscience LLC

Curated by ChEMBL
LigandPNGBDBM50059026(5'-Methyl-2'-(biphenylmethyl)-3'-(phenylmethyl)spi...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against recombinant human calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DP3PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Dart Neuroscience LLC

Curated by ChEMBL
LigandPNGBDBM50059026(5'-Methyl-2'-(biphenylmethyl)-3'-(phenylmethyl)spi...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DP3PubMed
LigandPNGBDBM50059026(5'-Methyl-2'-(biphenylmethyl)-3'-(phenylmethyl)spi...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of full length GST-tagged PDE1B (unknown origin) assessed as decrease in FAM-cAMP hydrolysis preincubated for 5 mins followed by FAM-cAMP ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DP3PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Banasthali University

Curated by ChEMBL
LigandPNGBDBM50059026(5'-Methyl-2'-(biphenylmethyl)-3'-(phenylmethyl)spi...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3NRMPubMed