null

SMILES COc1cc(C)cc(c1)-c1nn(CC#N)cc1-c1cc(NCCCO)nc(n1)-c1cccnc1

InChI Key InChIKey=GOIJYANVURFOJS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062382   

TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062382(CHEMBL3397285)copy SMILEScopy InChI
Affinity DataIC50: 5.09E+4nMAssay Description:Inhibition of ROS1 in human HCC78 cells after 48 hrs by CellTitre-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MX6PubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062382(CHEMBL3397285)copy SMILEScopy InChI
Affinity DataIC50: 4.32E+3nMAssay Description:Inhibition of ALK (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MX6PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50062382(CHEMBL3397285)copy SMILEScopy InChI
Affinity DataIC50: 119nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MX6PubMed