null

SMILES CN1[C@@H]2CCC1[C@@H]([C@@H](C2)c1ccccc1)c1ccccc1

InChI Key InChIKey=URXGPOFPBIBVGT-JIRNRHONSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50068478   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068478((2S,3R,5R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Binding affinity for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068478((2S,3R,5R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Binding affinity of compound on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068478((2S,3R,5R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataKi:  410nMAssay Description:Binding affinity on dopamine and serotonin transporters in striated membranes using [3H]- paroxetineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068478((2S,3R,5R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataKi:  753nMAssay Description:Binding affinity for Serotonin transporter was determined by [3H]5-HT (serotonin) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068478((2S,3R,5R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 7.69E+3nMAssay Description:Inhibitory activity on dopamine and serotonin transporters in striated membranes using [3H]- paroxetineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068478((2S,3R,5R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibitory activity determined for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068478((2S,3R,5R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibitory activity on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068478((2S,3R,5R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 823nMAssay Description:Inhibitory activity against Serotonin transporter was determined for [3H]5-HT (serotonin) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed