null

SMILES CN1[C@@H]2CCC1[C@@H]([C@@H](C2)c1ccc(F)cc1)c1ccccc1

InChI Key InChIKey=OTLCKVZWBLLFNJ-JIRNRHONSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50068481   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068481((2S,3R,5R)-3-(4-Fluoro-phenyl)-8-methyl-2-phenyl-8...)copy SMILEScopy InChI
Affinity DataKi:  4.60nMAssay Description:Binding affinity for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068481((2S,3R,5R)-3-(4-Fluoro-phenyl)-8-methyl-2-phenyl-8...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Binding affinity of compound on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068481((2S,3R,5R)-3-(4-Fluoro-phenyl)-8-methyl-2-phenyl-8...)copy SMILEScopy InChI
Affinity DataKi:  122nMAssay Description:Binding affinity for Serotonin transporter was determined by [3H]5-HT (serotonin) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068481((2S,3R,5R)-3-(4-Fluoro-phenyl)-8-methyl-2-phenyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 134nMAssay Description:Inhibitory activity against Serotonin transporter was determined for [3H]5-HT (serotonin) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068481((2S,3R,5R)-3-(4-Fluoro-phenyl)-8-methyl-2-phenyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibitory activity on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068481((2S,3R,5R)-3-(4-Fluoro-phenyl)-8-methyl-2-phenyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity determined for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed