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SMILES Cc1cccc2c1nc([nH]c2=O)-c1ccccc1

InChI Key InChIKey=WLZJEOODSSBWMB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50068758   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50068758(8-Methyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1247...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human tankyrase2 after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9SKCPubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50068758(8-Methyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1247...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of human tankyrase1 after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9SKCPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50068758(8-Methyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1247...)copy SMILEScopy InChI
Affinity DataIC50: 795nMAssay Description:Inhibition of PARP1 (unknown origin) after 1 hr by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9SKCPubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
The University

Curated by ChEMBL
LigandPNGBDBM50068758(8-Methyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1247...)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0FNKPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50068758(8-Methyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1247...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant IMPDH2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9SKCPubMed