null

SMILES CCCN(CC1CC1)c1cc(C)nc2c(c(C)nn12)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=MOFYZEYIRXKTQI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50071235   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50071235(CHEMBL65078 | Cyclopropylmethyl-[3-(2,4-dichloro-p...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Binding affinity to the cloned human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72GWPPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50071235(CHEMBL65078 | Cyclopropylmethyl-[3-(2,4-dichloro-p...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29WDRPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50071235(CHEMBL65078 | Cyclopropylmethyl-[3-(2,4-dichloro-p...)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RTCPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50071235(CHEMBL65078 | Cyclopropylmethyl-[3-(2,4-dichloro-p...)copy SMILEScopy InChI
Affinity DataIC50: 76nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z48DSPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50071235(CHEMBL65078 | Cyclopropylmethyl-[3-(2,4-dichloro-p...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29WDRPubMed