null
SMILES Cc1nc(C#Cc2ccnc(Cl)c2)c(C)n1-c1ccc(OC(F)(F)F)cc1
InChI Key InChIKey=GOHCTCOGYKAJLZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50071375
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 5.39E+5nMAssay Description:Experimental material: HEK293/mGluR5 cell line, Fluo-8 calcium ion fluorescent dye, positive control MPEP, CTEPExperimental instrument: FLIPR Tetra r...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair