null

SMILES Cc1nc(C#Cc2ccnc(Cl)c2)c(C)n1-c1ccc(F)cc1F

InChI Key InChIKey=OHTNGFRHJDYZSO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50071376   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50071376(CHEMBL3410224)copy SMILEScopy InChI
Affinity DataKi:  33nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J96825PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50071376(CHEMBL3410224)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J96825PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50071376(CHEMBL3410224)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J96825PubMed