null

SMILES CC(C)(C(CCc1ccccc1)NC(=O)c1ccc(cc1)C#N)C(=O)OC(=O)C(C)(C)C(CCc1ccccc1)NC(=O)c1ccc(cc1)C#N

InChI Key InChIKey=HQNCLEFIYXURJH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50073139   

TargetChymotrypsinogen B(Bos taurus)
Nippon Steel Corporation

Curated by ChEMBL
LigandPNGBDBM50073139(2-(4-cyanophenylcarboxamido)-1,1-dimethyl-4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930SBFPubMed
TargetSerine protease 1(Bos taurus (bovine))
Nippon Steel Corporation

Curated by ChEMBL
LigandPNGBDBM50073139(2-(4-cyanophenylcarboxamido)-1,1-dimethyl-4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Compound was tested by chromogenic assay for the inhibition of serine proteases like Bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930SBFPubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Nippon Steel Corporation

Curated by ChEMBL
LigandPNGBDBM50073139(2-(4-cyanophenylcarboxamido)-1,1-dimethyl-4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibitory activity against porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1BGCPubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Nippon Steel Corporation

Curated by ChEMBL
LigandPNGBDBM50073139(2-(4-cyanophenylcarboxamido)-1,1-dimethyl-4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1BGCPubMed
TargetCathepsin G(Homo sapiens (Human))
Nippon Steel Corporation

Curated by ChEMBL
LigandPNGBDBM50073139(2-(4-cyanophenylcarboxamido)-1,1-dimethyl-4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against human leukocyte cathepsin G (h-CG)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1BGCPubMed
TargetSerine protease 1(Homo sapiens (Human))
Nippon Steel Corporation

Curated by ChEMBL
LigandPNGBDBM50073139(2-(4-cyanophenylcarboxamido)-1,1-dimethyl-4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against porcine pancreatic trypsin (TRP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1BGCPubMed
TargetChymase(Homo sapiens (Human))
Nippon Steel Corporation

Curated by ChEMBL
LigandPNGBDBM50073139(2-(4-cyanophenylcarboxamido)-1,1-dimethyl-4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibitory activity against human chymase (h-chymase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1BGCPubMed