null

SMILES CN(C)Cc1ccccc1Sc1ccc(Br)cc1CO

InChI Key InChIKey=CHLYWPGOYPDIPF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50073438   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073438(CHEMBL278165 | [5-Bromo-2-(2-dimethylaminomethyl-p...)copy SMILEScopy InChI
Affinity DataKi:  0.520nMAssay Description:In vitro binding affinity of the compound against Serotonin transporter (SERT) from LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3DJNPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50073438(CHEMBL278165 | [5-Bromo-2-(2-dimethylaminomethyl-p...)copy SMILEScopy InChI
Affinity DataKi:  1.92nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetTransporter(Rattus norvegicus)
INSERM

Curated by ChEMBL
LigandPNGBDBM50073438(CHEMBL278165 | [5-Bromo-2-(2-dimethylaminomethyl-p...)copy SMILEScopy InChI
Affinity DataKi:  5.80nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine transporter (NET) of rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073438(CHEMBL278165 | [5-Bromo-2-(2-dimethylaminomethyl-p...)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:In vitro binding affinity of the compound against monoamine transporter NET (norepinephrine transporter) in LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3DJNPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50073438(CHEMBL278165 | [5-Bromo-2-(2-dimethylaminomethyl-p...)copy SMILEScopy InChI
Affinity DataKi:  950nMAssay Description:Inhibition of [3H]-GBR-12,935 binding to dopamine transporter (DAT) of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073438(CHEMBL278165 | [5-Bromo-2-(2-dimethylaminomethyl-p...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity of the compound against Dopamine transporter in LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3DJNPubMed