null

SMILES Fc1ccc(Nc2ncnc3cnc(NC(=O)C=C)cc23)cc1Cl

InChI Key InChIKey=CIGSBJHMSOROSY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077241   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077241(CHEMBL53555 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of epidermal growth factor receptor (EGFR) in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56HZGPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077241(CHEMBL53555 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 0.770nMAssay Description:Inhibition of phosphorylation of glutamic acid/tyrosine random copolymer by isolated epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56HZGPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077241(CHEMBL53555 | N-[4-(3-Chloro-4-fluoro-phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of heregulin-stimulated autophosphorylation of ERBB2 receptor kinase in MDA-MB-453 cells.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56HZGPubMed