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SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-1=[#6](-[#8])-[#6](=O)-[#6]=[#6](-[#8])-[#6]-1=O

InChI Key InChIKey=WLGCIQYXKPKVKY-YRNVUSSQSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50078880   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078880(CHEMBL3416167)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72K5HPubMed
TargetMacrophage-expressed gene 1 protein(Homo sapiens (Human))
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078880(CHEMBL3416167)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 synthase activity after 15 mins using ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72K5HPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078880(CHEMBL3416167)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72K5HPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078880(CHEMBL3416167)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72K5HPubMed