null

SMILES COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C(=C\C(C)(C)C)\C#N)c2)n1)N1CCN(C)CC1

InChI Key InChIKey=FSGZFPBFQNZABR-LVZFUZTISA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084030   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Technische Universit£t Dortmund

Curated by ChEMBL
LigandPNGBDBM50084030(CHEMBL3425666)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of wild type N-terminal His6-tagged human EGFR kinase domain (702 to 1016 residues) expressed in Sf9 cells pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9STHPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Technische Universit£t Dortmund

Curated by ChEMBL
LigandPNGBDBM50084030(CHEMBL3425666)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of GST-tagged human recombinant EGFR catalytic domain (668 to 1210 amino acids) T790M/L858R mutant expressed in Sf9 cells pre-incubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9STHPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Technische Universit£t Dortmund

Curated by ChEMBL
LigandPNGBDBM50084030(CHEMBL3425666)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of GST-tagged human recombinant EGFR catalytic domain (668 to 1210 amino acids) L858R mutant expressed in Sf9 cells pre-incubated for 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9STHPubMed