null
SMILES COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C(=C\c3ccc(cc3)N(C)C)\C(F)(F)F)c2)n1)N1CCN(C)CC1
InChI Key InChIKey=AZPQHHYAMDTQJO-IMRQLAEWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50084034
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Technische Universit£t Dortmund
Curated by ChEMBL
Technische Universit£t Dortmund
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of wild type N-terminal His6-tagged human EGFR kinase domain (702 to 1016 residues) expressed in Sf9 cells pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Technische Universit£t Dortmund
Curated by ChEMBL
Technische Universit£t Dortmund
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of GST-tagged human recombinant EGFR catalytic domain (668 to 1210 amino acids) T790M/L858R mutant expressed in Sf9 cells pre-incubated fo...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Technische Universit£t Dortmund
Curated by ChEMBL
Technische Universit£t Dortmund
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of GST-tagged human recombinant EGFR catalytic domain (668 to 1210 amino acids) L858R mutant expressed in Sf9 cells pre-incubated for 30 m...More data for this Ligand-Target Pair