null
SMILES CN1CCC(O)(C(C1)C(=O)c1ccc(C)cc1)c1ccc(C)cc1
InChI Key InChIKey=SWFNNRQTSSTAGB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50084716
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 360nMAssay Description:Inhibition of [3H]-DA Uptake at Dopamine transporter in rat cortex was measured by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 492nMAssay Description:Binding Affinity to cocaine site of Dopamine transporter in caudate nuclei which was homogenized and incubated with [3H]-mazindol .More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 1.63E+3nMAssay Description:Compound was tested for Inhibition of [3H]-5-HT Uptake in rat mid brain.More data for this Ligand-Target Pair
Affinity DataKi: 3.86E+3nMAssay Description:Compound was tested for Inhibition of [3H]-NE Uptake in rat parietal/occipital cortexMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.16E+3nMAssay Description:Antagonism of cocaine''s inhibition of [3H]-DA uptake at the dose of 500 nMMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Antagonism of cocaine''s inhibition of [3H]-DA uptake at the dose of 50 nMMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataIC50: 717nMAssay Description:Antagonism of cocaine''s inhibition of [3H]-DA uptake at the dose of 200 nMMore data for this Ligand-Target Pair