null

SMILES COc1cc2CCN(C(=O)Nc3cccnc3)c2cc1C(F)(F)F

InChI Key InChIKey=ROZXAOHUYCQNLS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50086058   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086058(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine receptor 2C in HEK293 cells, using [3H]mesulergine as radioligand.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X85V5PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086058(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 2C receptor expressed in HEK 293 cells using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1H48PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086058(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 2A receptor expressed in HEK 293 cells using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1H48PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086058(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine receptor 2A in HEK293 cells, using [3H]ketanserin as radioligand.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X85V5PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50086058(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of heterologously expressed human cytochrome P450 1A2.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X85V5PubMed