null

SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3nn(C4CCN(CC4)C(=O)C=C)c4ncnc(N)c34)cc2C(F)(F)F)CC1

InChI Key InChIKey=VRCBGBBYFHLJRE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50086442   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50086442(CHEMBL3426233 | US10266537, Compound 121)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38V91PubMed
TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM50086442(CHEMBL3426233 | US10266537, Compound 121)copy SMILEScopy InChI
Affinity DataIC50: 133nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetProto-oncogene tyrosine-protein kinase Src [1-530](Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM50086442(CHEMBL3426233 | US10266537, Compound 121)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM50086442(CHEMBL3426233 | US10266537, Compound 121)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM50086442(CHEMBL3426233 | US10266537, Compound 121)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM50086442(CHEMBL3426233 | US10266537, Compound 121)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent