null

SMILES Fc1ccc(Nc2ncnc3cc(\C=C\CCN4CCOCC4)c(NC(=O)C=C)nc23)cc1Cl

InChI Key InChIKey=DWKWPKBAUKFSKF-HWKANZROSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087082   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087082(CHEMBL417478 | N-[4-(3-Chloro-4-fluoro-phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 119nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087082(CHEMBL417478 | N-[4-(3-Chloro-4-fluoro-phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of autophosphorylation of ERBB2 receptor kinase in MDA-MB 453 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50087082(CHEMBL417478 | N-[4-(3-Chloro-4-fluoro-phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by imm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13179PubMed