null
SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)c2cccc(F)n2)cc1
InChI Key InChIKey=HAKZUMWJXAWWDO-SSEXGKCCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50089869
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
CNRS-Universit£ Montpellier I et Universit£ Montpellier II
Curated by ChEMBL
CNRS-Universit£ Montpellier I et Universit£ Montpellier II
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of 125I-[His9]-ghrelin from human GHSR1a expressed in LLC-PK1 cells by competitive binding assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
CNRS-Universit£ Montpellier I et Universit£ Montpellier II
Curated by ChEMBL
CNRS-Universit£ Montpellier I et Universit£ Montpellier II
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at GHSR1a (unknown origin) assessed as inhibition of ghrelin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
CNRS-Universit£ Montpellier I et Universit£ Montpellier II
Curated by ChEMBL
CNRS-Universit£ Montpellier I et Universit£ Montpellier II
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at human GSHR1a expressed in mouse LTK cells assessed as inhibition of ghrelin-induced reporter gene expression after 6 hrs by CR...More data for this Ligand-Target Pair