null
SMILES N#Cc1cc2c(cn1)[nH]c1ncc(cc21)-c1ccoc1
InChI Key InChIKey=KZSZKBQXNVVBFG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50091273
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Argenta Discovery Ltd.
Curated by ChEMBL
Argenta Discovery Ltd.
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant Chk1 using biotinylated AKT substrate after 30 mins by Alphascreen biochemical assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Argenta Discovery Ltd.
Curated by ChEMBL
Argenta Discovery Ltd.
Curated by ChEMBL
Affinity DataEC50: 180nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as phosphorylation of histone H3 after 24 hrs by checkpoint abrogation cellular assayMore data for this Ligand-Target Pair