null
SMILES NC(=O)c1cc2c(cn1)[nH]c1ncc(cc21)-c1ccc(CN2CCCCC2)cc1
InChI Key InChIKey=CJNHSOPFLMXKDT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50091307
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Argenta Discovery Ltd.
Curated by ChEMBL
Argenta Discovery Ltd.
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant Chk1 using biotinylated AKT substrate after 30 mins by Alphascreen biochemical assayMore data for this Ligand-Target Pair
Affinity DataIC50: 217nMAssay Description:Inhibition of human acetylcholine esterase by horseradish peroxidase-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Argenta Discovery Ltd.
Curated by ChEMBL
Argenta Discovery Ltd.
Curated by ChEMBL
Affinity DataEC50: 292nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as phosphorylation of histone H3 after 24 hrs by checkpoint abrogation cellular assayMore data for this Ligand-Target Pair