null
SMILES C(N1CCCCC1)c1ccc(cc1)-c1cnc2[nH]c3cnccc3c2c1
InChI Key InChIKey=AGJHYDCWZUUFAE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50091308
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Argenta Discovery Ltd.
Curated by ChEMBL
Argenta Discovery Ltd.
Curated by ChEMBL
Affinity DataEC50: 1.92E+3nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as phosphorylation of histone H3 after 24 hrs by checkpoint abrogation cellular assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Argenta Discovery Ltd.
Curated by ChEMBL
Argenta Discovery Ltd.
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant Chk1 using biotinylated AKT substrate after 30 mins by Alphascreen biochemical assayMore data for this Ligand-Target Pair