null

SMILES Cc1ccnc(N)c1

InChI Key InChIKey=ORLGLBZRQYOWNA-UHFFFAOYSA-N

PDB links: 3 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50091800   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)copy SMILEScopy InChI
Affinity DataIC50: 120nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)copy SMILEScopy InChI
Affinity DataIC50: 320nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB443QPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)copy SMILEScopy InChI
Affinity DataIC50: 160nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB443QPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibitory activity against neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319V30PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319V30PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102MTPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102MTPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of rat neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102MTPubMed