null

SMILES CC12CCC3C(CC=C4CC(O)CCC34C)C1CCC2CC1CN1

InChI Key InChIKey=KRFWHRJXDKUGAA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50094191   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of the Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Binding affinity for Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7FH3PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University of the Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Binding affinity for Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7FH3PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University of the Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7FH3PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
University of the Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of thromboxane synthase P450 TXA2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7FH3PubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
University of the Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of P450 sccMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7FH3PubMed
TargetAromatase(Homo sapiens (Human))
University of the Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7FH3PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of the Saarland

Curated by ChEMBL
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7FH3PubMed