null

SMILES CCOc1cc2ncnc(Nc3cccc(F)c3)c2cc1OCC

InChI Key InChIKey=VIZJVXABYUPLHN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095277   

TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50095277((6,7-Diethoxy-quinazolin-4-yl)-(3-fluoro-phenyl)-a...)copy SMILEScopy InChI
Affinity DataIC50: 9.20E+3nMAssay Description:Concentration required to inhibit the human liver recombinant fructose-1,6-bisphosphatase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W52PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095277((6,7-Diethoxy-quinazolin-4-yl)-(3-fluoro-phenyl)-a...)copy SMILEScopy InChI
Affinity DataIC50: 8.17nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095277((6,7-Diethoxy-quinazolin-4-yl)-(3-fluoro-phenyl)-a...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed