null

SMILES OC(=O)C(=O)CC(=O)c1cccc(Cc2ccccc2F)c1

InChI Key InChIKey=LORKTBWHCFDMKQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50095515   

TargetIntegrase(Human immunodeficiency virus 1)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50095515(4-[3-(2-Fluoro-benzyl)-phenyl]-2,4-dioxo-butyric a...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV-1 integrase catalytic activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P3136PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Max-Planck-Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50095515(4-[3-(2-Fluoro-benzyl)-phenyl]-2,4-dioxo-butyric a...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8SHKPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50095515(4-[3-(2-Fluoro-benzyl)-phenyl]-2,4-dioxo-butyric a...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant HIV-1 Integrase in strand transfer enzyme assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2930SFSPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50095515(4-[3-(2-Fluoro-benzyl)-phenyl]-2,4-dioxo-butyric a...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Evaluated for inhibition of HIV-1 integrase catalytic activity in terms of inhibition of 3'-processingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P3136PubMed