null

SMILES CCCn1cc(O)n([C@H]2C[C@@H](N(C2)S(=O)(=O)c2ccc(OCCOC)cc2)C(=O)NO)c1=O

InChI Key InChIKey=PILJHIOYYOZKRU-WMLDXEAASA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50095549   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095549(4-(2,5-Dioxo-3-propyl-imidazolidin-1-yl)-1-[4-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase -2 (gelatinase-A)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N80DWPubMed
TargetMatrilysin(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095549(4-(2,5-Dioxo-3-propyl-imidazolidin-1-yl)-1-[4-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-7 (matrilysin, MMP-7)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N80DWPubMed
TargetMatrilysin(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095549(4-(2,5-Dioxo-3-propyl-imidazolidin-1-yl)-1-[4-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571DBDPubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095549(4-(2,5-Dioxo-3-propyl-imidazolidin-1-yl)-1-[4-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase -3 (stromelysin)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N80DWPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095549(4-(2,5-Dioxo-3-propyl-imidazolidin-1-yl)-1-[4-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase -1 (collagenase-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N80DWPubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095549(4-(2,5-Dioxo-3-propyl-imidazolidin-1-yl)-1-[4-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against human recombinant matrix metalloproteinase-13 (collagenase-3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N80DWPubMed