null

SMILES NC(=O)CN1CCC(CC1)n1cc(-c2cccc(O)c2)c2c(N)ncnc12

InChI Key InChIKey=CHWHVQUNCYDPDK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50097979   

TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097979(2-(4-(4-amino-5-(3-hydroxyphenyl)-7H-pyrrolo[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of autophosphorylation of epidermal growth factor receptor (EGF-R) in a cellular assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097979(2-(4-(4-amino-5-(3-hydroxyphenyl)-7H-pyrrolo[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Concentration required for inhibition of epidermal growth factor receptor (EGF-R) by tyrosine kinase enzyme activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097979(2-(4-(4-amino-5-(3-hydroxyphenyl)-7H-pyrrolo[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Tested for inhibitory activity against Epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097979(2-(4-(4-amino-5-(3-hydroxyphenyl)-7H-pyrrolo[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097979(2-(4-(4-amino-5-(3-hydroxyphenyl)-7H-pyrrolo[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Concentration required for inhibition of c-Src mediated phosphorylation of Fak in IC8.1 fibroblast cell assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50097979(2-(4-(4-amino-5-(3-hydroxyphenyl)-7H-pyrrolo[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC8434PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50097979(2-(4-(4-amino-5-(3-hydroxyphenyl)-7H-pyrrolo[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of p60 c-Src tyrosine kinase enzyme activity in liquid-phase tyrosine phosphorylation assay at 830 ng/mLMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed