null

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NC(CC#Cc1ccccc1)C(O)=O

InChI Key InChIKey=UXURFMZZZWZYFW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50098263   

TargetCollagenase 3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098263(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-5-phenyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 21nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-13 in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN374TPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098263(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-5-phenyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-1 in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN374TPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098263(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-5-phenyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 12nMpH: 7.4Assay Description:Inhibitory activity against matrix metalloproteinase-2 (MMP-2) in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN374TPubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098263(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-5-phenyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 2.28E+3nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-3 (MMP-3) (at pH 7.4)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN374TPubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098263(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-5-phenyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89D47PubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098263(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-5-phenyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 20.9nMAssay Description:Inhibitory activity against recombinant human matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C24XK1PubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098263(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-5-phenyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89D47PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098263(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-5-phenyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 553nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89D47PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098263(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-5-phenyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 12.5nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89D47PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098263(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-5-phenyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.96E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89D47PubMed
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098263(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-5-phenyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89D47PubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098263(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-5-phenyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 2.28E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89D47PubMed