null
SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NC(CC#Cc1ccccc1)C(O)=O
InChI Key InChIKey=UXURFMZZZWZYFW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50098263
Affinity DataIC50: 21nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-13 in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-1 in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 12nMpH: 7.4Assay Description:Inhibitory activity against matrix metalloproteinase-2 (MMP-2) in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 2.28E+3nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-3 (MMP-3) (at pH 7.4)More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
Affinity DataIC50: 20.9nMAssay Description:Inhibitory activity against recombinant human matrix metalloprotease-13More data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataIC50: 553nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 12.5nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-2More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.96E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against matrix metalloprotease-7More data for this Ligand-Target Pair
Affinity DataIC50: 2.28E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3More data for this Ligand-Target Pair