null
SMILES COc1ccc(cc1)C#Cc1ccc(cc1)S(=O)(=O)NC(CC#CCN1CCOCC1)C(O)=O
InChI Key InChIKey=SBPZKNUSQCPAAY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50098274
Affinity DataIC50: 116nMpH: 7.4Assay Description:Inhibition of human matrix metalloproteinase-13 at pH 7.4More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 28nMpH: 7.4Assay Description:Inhibitory activity against matrix metalloproteinase-2 (MMP-2) in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 115nMAssay Description:Inhibitory activity against recombinant human matrix metalloprotease-13More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:Inhibition of human matrix metalloproteinase-1 at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-3 (MMP-3) (at pH 7.4)More data for this Ligand-Target Pair