null

SMILES COc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)NC(CC#Cc1ccccc1)C(O)=O

InChI Key InChIKey=ZSZSGGNFCMWYDF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50098299   

TargetInterstitial collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098299(2-[5-(4-Methoxy-phenylethynyl)-thiophene-2-sulfony...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:Inhibition of human matrix metalloproteinase-1 at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN374TPubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098299(2-[5-(4-Methoxy-phenylethynyl)-thiophene-2-sulfony...)copy SMILEScopy InChI
Affinity DataIC50: 1.01E+4nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-3 (MMP-3) (at pH 7.4)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN374TPubMed
TargetCollagenase 3(Homo sapiens (Human))
gvk bioSciences Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50098299(2-[5-(4-Methoxy-phenylethynyl)-thiophene-2-sulfony...)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Inhibitory activity against recombinant human matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C24XK1PubMed
TargetCollagenase 3(Homo sapiens (Human))
gvk bioSciences Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50098299(2-[5-(4-Methoxy-phenylethynyl)-thiophene-2-sulfony...)copy SMILEScopy InChI
Affinity DataIC50: 145nMpH: 7.4Assay Description:Inhibition of human matrix metalloproteinase-13 at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN374TPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098299(2-[5-(4-Methoxy-phenylethynyl)-thiophene-2-sulfony...)copy SMILEScopy InChI
Affinity DataIC50: 46nMpH: 7.4Assay Description:Inhibitory activity against matrix metalloproteinase-2 (MMP-2) in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN374TPubMed