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SMILES COc1cccc2CN(CCCc3c[nH]c4ccc(F)cc34)CCc12

InChI Key InChIKey=HKMJCOCCPVLYPB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50102012   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50102012(2-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-5-methoxy-1,...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GM86K9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Hadassah-Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102012(2-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-5-methoxy-1,...)copy SMILEScopy InChI
Affinity DataKi:  6.46nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q218368WPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Hadassah-Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102012(2-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-5-methoxy-1,...)copy SMILEScopy InChI
Affinity DataKi:  44.7nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q218368WPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Hadassah-Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102012(2-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-5-methoxy-1,...)copy SMILEScopy InChI
Affinity DataKi:  164nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q218368WPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Hadassah-Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102012(2-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-5-methoxy-1,...)copy SMILEScopy InChI
Affinity DataKi:  1.49E+3nMAssay Description:Displacement of [3H]WIN35,428 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q218368WPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Hadassah-Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50102012(2-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-5-methoxy-1,...)copy SMILEScopy InChI
Affinity DataKi:  2.88E+3nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q218368WPubMed