null

SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1

InChI Key InChIKey=DTRXURJDKOYCCD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 35 hits for monomerid = 50102712   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  2.19nMAssay Description:Ability to displace [3H]spiperone from dopamine receptor D4.4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M91PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0G5QPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Binding affinity against human dopamine receptor D4.4 using radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MWDPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  2.20nMMore data for this Ligand-Target Pair
In DepthDetails
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Biniding affinity for Dopamine receptor D4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131HWPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  2.70nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61M03PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0G5QPubMed
Target5-hydroxytryptamine receptor 2A(PIG)
Clinic of Nuclear Medicine

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  900nMAssay Description:Displacement of [3H]ketanserin from pig cortical membrane 5HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KMTPubMed
Target5-hydroxytryptamine receptor 2A(PIG)
Clinic of Nuclear Medicine

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  900nMAssay Description:Displacement of [3H]ketanserin from 5HT2 receptor in pig cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB75FFPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  1.31E+3nMAssay Description:Binding affinity against human Dopamine receptor D2 using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61M03PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0G5QPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN399WPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:Binding affinity for human dopamine receptor D2 longMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131HWPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:Binding affinity against dopamine receptor D2L using radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MWDPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0G5QPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of [3H]spiperone from cloned human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB75FFPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:Binding affinity to human dopamine D2 long receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KMTPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  5.30E+3nMAssay Description:Displacement of [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB75FFPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  5.30E+3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0G5QPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  5.30E+3nMAssay Description:Binding affinity for human dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H131HWPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  5.30E+3nMAssay Description:Binding affinity against dopamine receptor D3 using radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MWDPubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  5.30E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of human dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84FBZPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  5.30E+3nMAssay Description:Binding affinity to human D3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KMTPubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of human dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84FBZPubMed
TargetD(1A) dopamine receptor(Sus scrofa)
Clinic of Nuclear Medicine

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  5.50E+3nMAssay Description:Binding affinity to pig cortical membrane dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KMTPubMed
TargetD(1A) dopamine receptor(Sus scrofa)
Clinic of Nuclear Medicine

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  5.50E+3nMAssay Description:Displacement of [3H]SCH23990 from dopamine D1 receptor in pig striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB75FFPubMed
TargetD(1A) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  5.50E+3nMAssay Description:Binding affinity against dopamine receptor D1 using radioligand [3H]-SCH- 23390More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MWDPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84FBZPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  6.30E+3nMAssay Description:Displacement of [3H]spiperone from cloned human dopamine D2S receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB75FFPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  6.30E+3nMAssay Description:Binding affinity against dopamine receptor D2S using radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MWDPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  6.30E+3nMAssay Description:Inhibition of human dopamine D2 (short) receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84FBZPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  8.30E+3nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0G5QPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50102712(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)copy SMILEScopy InChI
Affinity DataEC50:  154nMAssay Description:Effective concentration against human Dopamine receptor D4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61M03PubMed