null
SMILES CC(C)CC(C\C=C1\CC(CO)(COC(=O)C(C)(C)C)OC1=O)CC(C)C
InChI Key InChIKey=XKEOGEXDEKIDNA-NVMNQCDNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50107112
Affinity DataKi: 1.15nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 1.16nM ΔG°: -11.9kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of [3H]-PDBu binding to C1b domain of protein kinase C deltaMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity for isolated C1b domain of protein kinase C-deltaMore data for this Ligand-Target Pair
Affinity DataKi: 1.21nMAssay Description:Binding affinity to mouse wildtype PKCdelta C1a expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute at Frederick
Curated by ChEMBL
National Cancer Institute at Frederick
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Binding affinity for Protein kinase C alpha C1a or C1b domainMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute at Frederick
Curated by ChEMBL
National Cancer Institute at Frederick
Curated by ChEMBL
Affinity DataKi: 2.90nMpH: 7.4Assay Description:Inhibition of [3H]PDBu binding to recombinant protein kinase C alpha was determined at pH 7.4, 37 degree C for 5 minMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute at Frederick
Curated by ChEMBL
National Cancer Institute at Frederick
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]PDBu from mouse recombinant PKCalpha expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute at Frederick
Curated by ChEMBL
National Cancer Institute at Frederick
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Displacement of [20-3H]-PDBU ligand from recombinant protein kinase C (baculovirus)More data for this Ligand-Target Pair
Affinity DataKi: 44.8nMAssay Description:Displacement of [3H]PDBu from mouse PKCdelta C1b Q27E mutant expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute at Frederick
Curated by ChEMBL
National Cancer Institute at Frederick
Curated by ChEMBL
Affinity DataKi: 402nM ΔG°: -8.51kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
Affinity DataKi: 476nMAssay Description:Binding affinity to mouse PKC delta C1a Q27E mutant expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 1.03E+3nM ΔG°: -7.97kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
Affinity DataKi: 1.07E+3nM ΔG°: -7.95kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair