null

SMILES OC(=O)[C@H]1CC[C@H](CNc2nc3ccc(cc3s2)-c2ccn(CC3CC3)c(=O)c2)CC1

InChI Key InChIKey=LCUPEZBPGVQFLN-JCNLHEQBSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50107257   

LigandPNGBDBM50107257(CHEMBL3600785)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PI3Kbeta (unknown origin) pre-incubated for 20 mins before phosphatidylinositol 4, 5-bisphosphate substrate addition by kinase-glo plus...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DKRPubMed
LigandPNGBDBM50107257(CHEMBL3600785)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin) pre-incubated for 20 mins before phosphatidylinositol 4, 5-bisphosphate substrate addition by kinase-glo plu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DKRPubMed
LigandPNGBDBM50107257(CHEMBL3600785)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PI3Kalpha (unknown origin) pre-incubated for 20 mins before phosphatidylinositol 4, 5-bisphosphate substrate addition by kinase-glo plu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DKRPubMed
TargetPhosphatidylinositol 4-kinase beta(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50107257(CHEMBL3600785)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:Inhibition of N-terminal GST-tagged human full length recombinant PI4K3beta expressed in Sf9 cells using D-myo-phosphatidylinositol substrate and ATP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DKRPubMed
TargetPhosphatidylinositol 4-kinase alpha(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50107257(CHEMBL3600785)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length recombinant PI4K3alpha using D-myo-phosphatidylinositol substrate and ATP incubated for 45 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DKRPubMed
LigandPNGBDBM50107257(CHEMBL3600785)copy SMILEScopy InChI
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of PI3Kdelta (unknown origin) pre-incubated for 20 mins before phosphatidylinositol 4, 5-bisphosphate substrate addition by kinase-glo plu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DKRPubMed