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SMILES COC1Cc2ccccc2C2(CCN(CCCc3ccccc3)CC2)O1

InChI Key InChIKey=IJKYJDDNDXAREJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50108654   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Pharmazeutisches Institut der Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM50108654(1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Sigma opioid receptor type 1 affinity in guinea pig brain by employing [3H](+)-pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1RDHPubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Pharmazeutisches Institut der Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM50108654(1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...)copy SMILEScopy InChI
Affinity DataKi:  307nMAssay Description:Sigma opioid receptor type 2 affinity in rat liver by employing [3H]ditolylguanidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1RDHPubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Pharmazeutisches Institut der Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM50108654(1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MK 801 binding to NMDA, PCP receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1RDHPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Pharmazeutisches Institut der Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM50108654(1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of mepyramine binding to Histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1RDHPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Pharmazeutisches Institut der Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM50108654(1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I][MePhe7]-NKB binding to human Tachykinin receptor 3 (NK3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1RDHPubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pharmazeutisches Institut der Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM50108654(1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]-NKA binding to human Tachykinin receptor 2 (NK2)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1RDHPubMed
TargetD(1A) dopamine receptor(Mus musculus (Mouse))
Pharmazeutisches Institut der Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM50108654(1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SCH 23390 binding to Dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1RDHPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pharmazeutisches Institut der Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM50108654(1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of ketanserin binding to 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1RDHPubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Pharmazeutisches Institut der Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM50108654(1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of idazoxane binding to noradrenaline alpha-2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1RDHPubMed
TargetGlycine receptor subunit alpha-4(Mus musculus)
Pharmazeutisches Institut der Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM50108654(1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MDL 105519 binding to NMDA, glycine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1RDHPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Pharmazeutisches Institut der Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM50108654(1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1RDHPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pharmazeutisches Institut der Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM50108654(1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:The compound was tested for inhibition of dopamine reuptakeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1RDHPubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Pharmazeutisches Institut der Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM50108654(1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 5-OH-DPAT binding to 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1RDHPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pharmazeutisches Institut der Universität Freiburg

Curated by ChEMBL
LigandPNGBDBM50108654(1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [Sar9,Met(O2)11]-SP binding to human Tachykinin receptor 1 (NK1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1RDHPubMed