null
SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)C#N)CC1
InChI Key InChIKey=STIRDGXSGQTCAJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50109943
Affinity DataKi: 1.5nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D4 stably expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataKi: 2.20E+3nMAssay Description:Compound was tested in vitro for its ability to compete with [3H]8-OH-DPAT at 5-hydroxytryptamine 1A receptor in porcine brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D1 stably expressed in CHO cells by [3H]-SCH- 23390 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 2.60E+4nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D3 stably expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
In DepthDetails
Affinity DataKi: 4.40E+4nMAssay Description:Binding affinity of compound was tested in vitro for its ability to compete with [3H]spiperone radioligand at cloned human Dopamine receptor D2L stab...More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D2 (short) stably expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Tested for the effective concentration against human D4.2 receptor in CHO 10001 cells established in mitogenesis assayMore data for this Ligand-Target Pair