null

SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)C#N

InChI Key InChIKey=MFGYZKGJWDJWAA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50109945   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50109945(3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-met...)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D4 stably expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B5XPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50109945(3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-met...)copy SMILEScopy InChI
Affinity DataKi:  4.50E+3nMAssay Description:Compound was tested in vitro for its ability to compete with [3H]8-OH-DPAT at 5-hydroxytryptamine 1A receptor in porcine brain homogenateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B5XPubMed
TargetD(1A) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50109945(3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-met...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+4nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D1 stably expressed in CHO cells by [3H]-SCH- 23390 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B5XPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50109945(3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-met...)copy SMILEScopy InChI
Affinity DataKi:  2.10E+4nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D3 stably expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B5XPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50109945(3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-met...)copy SMILEScopy InChI
Affinity DataKi:  5.80E+4nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D2 (short) stably expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B5XPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50109945(3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-met...)copy SMILEScopy InChI
Affinity DataKi:  5.90E+4nMAssay Description:Binding affinity of compound was tested in vitro for its ability to compete with [3H]spiperone radioligand at cloned human Dopamine receptor D2L stab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B5XPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50109945(3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-met...)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Tested for the effective concentration against human D4.2 receptor in CHO 10001 cells established in mitogenesis assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B5XPubMed