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SMILES CC(c1ccccc1)c1ccc(cc1)C(=O)NCc1c(C)cc(C)[nH]c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50110371   

TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Constellation Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50110371(CHEMBL3605441)copy SMILES
Affinity DataIC50: 795nMAssay Description:Inhibition of EZH2 Y641N mutant (unknown origin) using biotinylated nucleosome, H3K27me3 activator and [3H]-SAM incubated for 60 mins by top-count ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q24205PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Constellation Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50110371(CHEMBL3605441)copy SMILES
Affinity DataIC50: 0.795nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D3059PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Constellation Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50110371(CHEMBL3605441)copy SMILES
Affinity DataIC50: 0.153nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D3059PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Constellation Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50110371(CHEMBL3605441)copy SMILES
Affinity DataIC50: 153nMAssay Description:Inhibition of EZH2 (unknown origin) using biotinylated nucleosome, H3K27me3 activator and [3H]-SAM incubated for 60 mins by top-count based methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q24205PubMed