null

SMILES Nc1ccccc1NC(=O)c1ccc(CNC2=NC[C@H](O2)c2ccccc2)cc1

InChI Key InChIKey=HIKRXEASUUGCMM-NRFANRHFSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50113963   

TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50113963(CHEMBL3605502)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Inhibition of C-flagged recombinant HDAC1 (unknown origin) pre-incubated for 1 hr before substrate addition by homogeneous fluorogenic HDAC assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0PFVPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50113963(CHEMBL3605502)copy SMILEScopy InChI
Affinity DataIC50: 1.73E+5nMAssay Description:Inhibition of His-flagged recombinant HDAC8 (unknown origin) expressed in Escherichia coli BL21 pre-incubated for 15 mins before substrate addition b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0PFVPubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50113963(CHEMBL3605502)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant HDAC3/NCOR2 (unknown origin) pre-incubated for 3 hrs before substrate addition by homogeneous fluorogenic HDAC assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0PFVPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50113963(CHEMBL3605502)copy SMILEScopy InChI
Affinity DataIC50: 192nMAssay Description:Inhibition of His-tagged recombinant HDAC2 (1 to 488 residues) (unknown origin) pre-incubated for 3 hrs before substrate addition by homogeneous fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0PFVPubMed