null

SMILES CC(C)NC(=O)C[C@H]1CCCN(C(=O)c2ccc(cc2Cl)N2CCCC2)c2ccccc12

InChI Key InChIKey=INGXCNVWWKKWOO-LJQANCHMSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50117486   

TargetVasopressin V2 receptor(Homo sapiens (Human))
UMR7200 CNRS/Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50117486(2-[(R)-1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,...)copy SMILEScopy InChI
Affinity DataKi:  92nMAssay Description:Displacement of [3H]-AVP from human V2 receptor expressed in human HeLa cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0HRFPubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
UMR7200 CNRS/Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50117486(2-[(R)-1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,...)copy SMILEScopy InChI
Affinity DataKi:  819nMAssay Description:Displacement of [3H]-AVP from human V1A receptor expressed in human HeLa cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0HRFPubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
UMR7200 CNRS/Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50117486(2-[(R)-1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]-AVP from human V1B receptor expressed in human HeLa cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0HRFPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
UMR7200 CNRS/Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50117486(2-[(R)-1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Binding affinity of the compound against human Vasopressin V2 receptor expressed in HeLa cells was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QRKPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50117486(2-[(R)-1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Binding affinity against Vasopressin V2 receptor was determined in Brattleboro ratsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QRKPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
UMR7200 CNRS/Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50117486(2-[(R)-1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,...)copy SMILEScopy InChI
Affinity DataEC50:  189nMAssay Description:Agonist activity at human V2 receptor expressed in human HeLa cells assessed as stimulation of cAMP accumulation by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0HRFPubMed