null

SMILES CCOc1ccc(cc1-c1nc2n(CC(C)C)c(=O)n(C)c(=O)c2[nH]1)S(=O)(=O)N1CCN(C)CC1

InChI Key InChIKey=VQWKJQIMZSXOOI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50117701   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50117701(8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against human platelet Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5FC2PubMed
LigandPNGBDBM50117701(8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)copy SMILEScopy InChI
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1 (PDE1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5FC2PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50117701(8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5FC2PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50117701(8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human platelet Phosphodiesterase 3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5FC2PubMed