null

SMILES O=C1Nc2ccc(cc2C11CCCCC1)-c1cccc(c1)C#N

InChI Key InChIKey=LCGYUHWSQNIRBE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50121163   

TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121163(3-(2'-oxo-1',2'-dihydrospiro[cyclohexane-1,3'-indo...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Progesterone receptor antagonist activity based on its ability to block progesterone induced alkaline phosphatase in the human breast cancer cell lin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R210RCPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121163(3-(2'-oxo-1',2'-dihydrospiro[cyclohexane-1,3'-indo...)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34Z1KPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121163(3-(2'-oxo-1',2'-dihydrospiro[cyclohexane-1,3'-indo...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44R56PubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121163(3-(2'-oxo-1',2'-dihydrospiro[cyclohexane-1,3'-indo...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44R56PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121163(3-(2'-oxo-1',2'-dihydrospiro[cyclohexane-1,3'-indo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity for androgen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34Z1KPubMed