null
SMILES COc1cc(NC(=O)\C=C\CN(C)C)cc2c(Nc3cccc(Br)c3)c(cnc12)C#N
InChI Key InChIKey=MPNMKIMGGUGYMJ-VMPITWQZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50122561
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.88E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
Affinity DataIC50: 2.88E+6nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 9.35E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of human epidermal growth factor receptor-2More data for this Ligand-Target Pair
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibition autophosphorylation of EGFR in human DiFi cells after 2 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibition of autophosphorylation of cytoplasmic domain of epidermal growth factor receptorMore data for this Ligand-Target Pair