null

SMILES Oc1c(ncc2cccnc12)C(=O)c1cc(CN2CCCS2(=O)=O)cc(Cc2ccccc2)c1

InChI Key InChIKey=UMPCIKHDGHZMJR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50123468   

TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123468(CHEMBL32865 | [3-Benzyl-5-(1,1-dioxo-1lambda 6 -is...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Compound was tested for its ability to inhibit the strand transfer of the integration process catalyzed by HIV integraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6HRGPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123468(CHEMBL32865 | [3-Benzyl-5-(1,1-dioxo-1lambda 6 -is...)copy SMILEScopy InChI
Affinity DataEC50: >800nMAssay Description:Potency of compound was tested against HIV-1- containing integrase mutations (T66I, S153Y)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6HRGPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123468(CHEMBL32865 | [3-Benzyl-5-(1,1-dioxo-1lambda 6 -is...)copy SMILEScopy InChI
Affinity DataEC50:  140nMAssay Description:Potency of compound was tested against HIV-1- containing integrase mutations (NL4-3)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6HRGPubMed
TargetIntegrase(Human immunodeficiency virus 1)
K.L.E.S. College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50123468(CHEMBL32865 | [3-Benzyl-5-(1,1-dioxo-1lambda 6 -is...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P9255PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123468(CHEMBL32865 | [3-Benzyl-5-(1,1-dioxo-1lambda 6 -is...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B858PNPubMed
TargetIntegrase(Human immunodeficiency virus 1)
K.L.E.S. College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50123468(CHEMBL32865 | [3-Benzyl-5-(1,1-dioxo-1lambda 6 -is...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity by high throughput electrochemiluminescent assay in presence of magnesiumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8B3PPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123468(CHEMBL32865 | [3-Benzyl-5-(1,1-dioxo-1lambda 6 -is...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against integrase-catalysed strand transferMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5MPJPubMed