null
SMILES CCCCCCCC(=O)SCC\C=C\[C@@H]1CC(=O)NCc2nc(cs2)C(=O)N\C(=C/C)C(=O)N[C@@H](C(C)C)C(=O)O1
InChI Key InChIKey=WCZYLKXWWUKEBA-QUDUTUPQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 50123628
TargetHistone deacetylase 6(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 6.95E+3nMAssay Description:Inhibition of recombinant human HDAC6 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant human N-terminal FLAG tagged HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 insect cells using fluorogeni...More data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC11 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of recombinant human HDAC3 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant human HDAC1 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC7 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC9 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 2.71E+3nMAssay Description:Inhibition of recombinant human HDAC2 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC8 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC4 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC5 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full length HDAC11 expressed in baculovirus infected Sf9 cells measured after 60 mins by FRET assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluorometric substrate measu...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of recombinant human full length C-terminal His- tagged HDAC2 (1 to 488 residues) expressed in Sf9 insect cells using fluorometric substra...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 3.96E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cells using fluorometric substra...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 (627 to 1084 residues) expressed in baculovirus infected Sf9 insect...More data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC5 expressed in baculovirus infected Sf9 insect cells using fluorogenic substrat...More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HDAC7 expressed in baculovirus infected Sf9 insect cells using fluorogenic substrate measured a...More data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC9 (604 to 1066 residues) expressed in baculovirus infected Sf9 insect cells using fluorogen...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institute of Biomedicine and Health
Curated by ChEMBL
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in Sf9 cells using fluorogenic substrate measured after 60 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of recombinant human HDAC10 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair