null

SMILES COc1ccc(NS(=O)(=O)c2ccc(\C=C\C(=O)NO)cc2)cc1OC

InChI Key InChIKey=IMQKXTRDVUWCMO-BJMVGYQFSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50123958   

TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene Inc.

US Patent
LigandPNGBDBM50123958(3-[4-(3,4-Dimethoxy-phenylsulfamoyl)-phenyl]-N-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 60nMT: 2°CAssay Description:For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B8WQWUS Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
Aton Pharma, Inc

Curated by ChEMBL
LigandPNGBDBM50123958(3-[4-(3,4-Dimethoxy-phenylsulfamoyl)-phenyl]-N-hyd...)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of acetylation of histone-4 in human T-24 cancer cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP5413PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene Inc.

US Patent
LigandPNGBDBM50123958(3-[4-(3,4-Dimethoxy-phenylsulfamoyl)-phenyl]-N-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against human Histone deacetylase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP5413PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene Inc.

US Patent
LigandPNGBDBM50123958(3-[4-(3,4-Dimethoxy-phenylsulfamoyl)-phenyl]-N-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory activity on partially purified recombinant human Histone deacetylase 1 (HDAC-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2FG8PubMed